HEALTH | Botox Injections May Reduce Depression, Study Finds

People who received Botox (Botulinum Toxin) injections for certain conditions reported less depression less often compared to patients who did not receive the injections for similar diagnoses, according to a study published Thursday in the journal Scientific Reports.

‘For years, clinicians have observed that Botox injected for cosmetic reasons seems to ease depression for their patients’, said Ruben Abagyan, Ph.D., professor of pharmacy and one of the lead researchers of the study, in a statement.

‘It’s been thought that easing severe frown lines in the forehead region disrupts a feedback loop that reinforces negative emotions. But we’ve found here the mechanism may be more complex because it doesn’t really matter where the Botox is injected’, the author stated in a news release.

The research team at Skaggs School of Pharmacy and Pharmaceutical Science at University of California San Diego combed through the U.S. Food and Drug Administration (FDA)’s Adverse Effect Reporting System (FEARS) database to see the side effects reported by nearly 40,000 people who received Botox injections for various reasons, according to a news release by the university.

The treatments were not just the forehead but included several different sites, including the neck, limbs and forehead. The release stated the researchers used an algorithm to find significant statistical difference between patients who used Botox and those who did not for the same issue.

The researcher found depression was reported 40 to 88 percent less often by Botox users for six of the eight conditions and injection sites, according to the release.

‘This finding is because it supports a new treatment to affect mood and fight depression, one of the common and dangerous mental illnesses – and it’s based on a very large body of statistical data, rather than limited – scale observations’, Tigran Makunts, PharmD. One of the researchers in the study, stated in the release.

More research is needed to determine how Botox potentially acts as an antidepressant, according to the study. The researchers have a few theories that need further investigation. For instance, Botox absorbed systemically to the central nervous system, which is involved in mood or emotions, they hypothesized or possibly Botox indirectly affecting a person’s depression because the Botox helped relieve an underlying chronic condition that may have been a contributing factor to the patient’s depression.

Health experts say Botox is commonly used not only for cosmetic reasons, such as combatting wrinkles but also for muscles spasm, tight muscles, migraines, temporomandibular joint dysfunction, as well as other condition including excessive sweating and bladder conditions.

The FAERS data used in this study was not exclusively gathered for the purpose of investigating the link between Botox and depression, according to the news release. The data represents only a subgroup of Botox users who reported experiencing negative side effects. The authors note they excluded data from patients who were taking antidepressants; however, in some of the cases, the use of medications could have been underreported.

The release stated there is a clinical trial underway that is directly investing Botox treatment for people with depression, but it is only testing forehead injection site is best to specifically inject to treat depression.

According to the World Health Organization, an estimated more than 264 million people worldwide experience depression.

Does Ingestible Collagen Work?

The ingestible collagen boom began several years ago, ans still shows no signs of abating. In fact, it’s been given yet another bump by avid TikTokkers touting its beauty benefits as ever more options pour into the marketplace. Among the promises: It will bless you with dewy, plump skin, strong nails, supple joints, even healthier … Continue reading Does Ingestible Collagen Work?

Cate Blanchett Sees Pandemic As Chance For Refelction On Plight Of Refugees

This year’s World Refugee Day offers a chance to reflect on the uncertainty faced by those forced to flee their homes, actor Cate Blanchett, a goodwill ambassador for the U.N. refugee agency, says as the world grapples with the unpredictability of the COVID-19 pandemic. The Oscar winner and UNHCR goodwill said  the annual June 20 … Continue reading Cate Blanchett Sees Pandemic As Chance For Refelction On Plight Of Refugees

7 Health Benefits Of Cherries

It’s cherry season again! They’re fresh, plentiful, beautiful, and delicious, but, you may be wondering – are cherries actually that good for you? The answer is yes, 100 times yes! Cherries are not only one of the healthiest fruits, they also rank as one of the most health protective foods overall. One cup, or about … Continue reading 7 Health Benefits Of Cherries

When Is The Best Time Of Day To Drink Coffee In Order To Boost Productivity?

Coffee lovers will tell you that every time of day is the best time to drink coffee; however experts say that there is an ideal time to sip a cup of joe in order to really reap the benefits of that caffeine boost. ‘If you are someone who has average tolerance to caffeine, then after having coffee, whether it’s … Continue reading When Is The Best Time Of Day To Drink Coffee In Order To Boost Productivity?

Loading…

Something went wrong. Please refresh the page and/or try again.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s